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  • Kilobaser allows scientists to custom-make specific molecules helping with studying diseases, developing new medicines, or even genetically modified organisms.
  • Briefcase Biotec plans to sell 1,000 kilobases per year worldwide from 2019.
  • Kilobaser was also mentioned among the top 90 Biotechnology startups in Austria (2021).

DNA is the blueprint of all lifeforms, and deciphering its code is critical. Being able to create DNA molecules will make headway in terms of research and advancement in the medical industry.

This is where a DNA Synthesizer plays its role. It can be compared to a fancy 3D printer but for molecules! It takes the code fed to it and builds the DNA molecule one piece at a time.

Kilobaser : The DNA Nespresso Machine

"DNA is the foundation of life science – why can’t we synthesize DNA ourselves?", was the question that circled around CEO and founder Alexander Murer's head.

Before Kilobaser, to obtain DNA molecules, scientists often had to depend on large companies and then have to wait for days or even weeks for it to be delivered. This most definitely hindered and slowed down the research process and its progress.

Taking inspiration from a Nespresso machine, founders Alexander Murer, Martin Jost, and Bernhard Tittlebach came up with the solution - a user-friendly and affordable printer that could directly synthesize DNA in the lab!

Briefcase Boiotec, founded in 2014 in Graz, Austria, had but one vision in mind for the Kilobaser: give researchers everywhere the ability to create custom DNA molecules faster, easier, and on demand.

Kilobaser's impact is more than just speed, its innovative design uses disposable cartridges and microfluidic technology, which is a miniaturized system that controls the fluids on a microchip accurately.

This technology allows researchers to synthesize DNA primers - short strands of DNA, crucial starting points for research with DNA - directly in their labs within an hour. With such a dramatic reduction in waiting time, going from days to hours, Kilobaser's presence in the market is a game changer.

Due to its affordability and user-friendly interface, it can be used in smaller labs and academic institutions that may not have access to traditional methods; allowing a wider range of scientists to participate in revolutionary discoveries.

The company didn't put a full stop there. In 2018, four years after its creation, Kilobaser launched its first Kilobaser Series 0 machines.

Their microfluidic LOC (lab-on-a-chip) technology offers considerable advantages over traditional organic chemistry-based synthesizers.

It boasts a 100-fold reduction in reagent consumption through its cartridge system, enabling the synthesis of DNA, RNA, probes, and modified oligos directly at the researcher's fingertips.

Aware of the global potential of their technology, Kilobaser chose to expand, partnering with Focus Academy, by opening a U.S. office; to streamline support and distribution with American researchers making Kilobaser globally accessible.

Kilobaser also appointed Meiwafosis as their exclusive distributor in Japan.

The global DNA synthesizer market is expected to reach over $754 million by 2031, underlining the increasing demand for this revolutionizing technology.

With its Kilobaser system, Briefcase Biotec is well-positioned to be a key player in this exciting and rapidly evolving field.


Edited by Annette George

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